Theme 1

Development of innovative technologies and research infrastructure

●: Principal Investigator 〇: Co-Investigator

[1A-01]

New synaptic chemogenetic manipulation for multi-species multi-level cross-sectional neuroscience

• Haruo Kasai
  Professor, International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo
• Siqi Zhou
  Project Researcher, WPI-IRCN, The University of Tokyo
• Takeshi Sawada
  Assistant Professor, The University of Tokyo Graduate School of Medicine
• Sho Yagishita
  Lecturer, The University of Tokyo Graduate School of Medicine
• Shinichiro Terada
  Assistant Professor, The University of Tokyo Graduate School of Medicine
• Takayuki Hashimoto
  Assistant Professor, The University of Tokyo Graduate School of Medicine
• Nami Kitajima
  Project Researcher, The University of Tokyo Graduate School of Medicine
• Tetsuo Yamamori
  Advisor, Department of Marmoset Biology and Medicine, Central Institute for Experimental Medicine and Life Sciences

[1A-02]

Development of Alzheimer’s disease model research platform

• Erika Sasaki
  Director, Department of Marmoset Biology and Medicine, Central Institute for Experimental Medicine and Lif Science
• Kazuhiko Seki
  Director, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Yasuhiro Go
  Professor, Exploratory Research Center on Life and Living System, National Institute of Natural Science

[1A-03]

Development of viral vector technology to strongly promote integrative neuroscience research

• Hirokazu Hirai
  Professor, Gunma University Graduate School of Medicine
• Ichiro Matsuo
  Professor, Gunma University Graduate School of Science and Technology
• Hiroyuki Hioki
  Professor, Juntendo University Graduate School of Medicine
• Kazuto Kobayashi
  Professor, Fukushima Medical University School of Medicine
• Ken-ichi Inoue
  Assistant Professor, Center for the Evolutionary Origins of Human Behavior, Kyoto University
• Sachiko Okamoto
  General Manager, Technology Development Center, Takara Bio Inc.

[1B-01]

Enhancement of the research basis and elucidation of the disease trajectory of Parkinson’s disease through the unification of a prodromal cohort study and multi-omics researches

• Yuji Takahashi
  Director, National Center Hospital, National Center of Neurology and Psychiatry
• Etsuro Nakanishi
  Assistant Professor, Kyoto University Hospital
• Ayami Okuzumi
  Associate Professor, Juntendo University Faculty of Medicine
• Hideki Mochizuki
  Professor, Osaka University Graduate School of Medicine
• Masahisa Katsuno
  Professor, Nagoya University Graduate School of Medicine
• Takeshi Ikeuchi
  Professor, Brain Research Institute, Niigata University

[1B-02]

Integrated spatiotemporal trans-scale imaging of brain function led by advanced laser light technology

• Tomomi Nemoto
  Professor, The Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences
• Yuichi Kozawa
  Professor, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University
• Kohei Otomo
  Associate Professor, Juntendo University Graduate School of Medicine

[1S-01]

Advanced multi-areal spike analysis for higher-order brain function in marmosets

• Yoshikazu Isomura
  Professor, Institute of Science Tokyo Graduate School of Medical and Dental Sciences
• Masami Kanai
  Professor, Institute of Science Tokyo Graduate School of Medical and Dental Sciences
• Yutaka Sakai
  Professor, Brain Science Institute, Tamagawa University
• Hideaki Shimazaki
  Associate Professor, Kyoto University Graduate School of Informatics

[1S-02]

Development of novel mouse models of Lewy body disease and seed propagation system in collaboration with structural biology

• Norihito Uemura
  Junior Assistant Professor, Osaka Metropolitan University Graduate School of Medicine
• Atsushi Yamagata
  Senior Scientist, RIKEN Center for Biosystems Dynamics Research

[1S-03]

High-speed, wide-field, and high-resolution imaging in marmoset motor cortex

• Teppei Ebina
  Lecturer, The University of Tokyo Graduate School of Medicine
• Masanori Matsuzaki
  Professor, The University of Tokyo Graduate School of Medicine

[1S-04]

Development of Innovative Nanosheets as Next-Generation Soft Cranial Windows for Brain Imaging

• Yosuke Okamura
  Professor, Micro/Nano Technology Center/School of Engineering, Tokai University
• Taiga Takahashi
  Assistant Professor, Tokyo University of Science Faculty of Advanced Engineering
• Masatoshi Yoshida
  Professor, Center for Human Nature, Artificial Intelligence, and Neuroscience, Hokkaido University.

[1S-05]

Development of 5D neural circuit analysis using a novel viral vector

• Fumitaka Osakada
  Associate Professor, Nagoya University Graduate School of Pharmaceutical Sciences

[1S-06]

Diverse neurotransmitter release dynamics controlling behavior

• Takaaki Ozawa
  Assistant Professor, Institute for protein research, Osaka university

[1S-07]

Investigation of the glymphatic dynamics in the brain and its involvement in neurological diseases

• Hiroshi Kawasaki
  Professor, Kanazawa University Graduate School of Medical Science
• Mitsutoshi Nakada
  Professor, Kanazawa University Graduate School of Medical Science

[1S-08]

Study on seamless analysis of functional and structural connectome of cortical microcircuits.

• Yoshiyuki Kubota
  Associate Professor, National Institute for Physiological Sciences, National Institutes of Natural Sciences
• Yasuhiro Tanaka
  Professor, Brain Science Institute, Tamagawa University

[1S-09]

Development of a Misfolded Protein Phagocytosis Targeting System for the Treatment of Neurodegenerative Diseases

• Ryuta Koyama
  Director, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP)

[1S-10]

Establishment of ultraviolet optogenetics

• Wataru Shihoya
  Assistant professor, The University of Tokyo Graduate School of Science
• Shunki Takaramoto
  Project researcher, Institute for Solid state physics, The University of Tokyo

[1S-11]

Versatile cell-type-specific AAV vectors for molecular and circuit manipulations

• Kaoru Seiriki
  Assistant professor, Osaka University Graduate School of Pharmaceutical Sciences

[1S-12]

Development of a versatile skull clearing method and its application to live imaging

• Kazuki Tainaka
  Professor, Brain Research Institute, Niigata University
• Takayasu Mikuni
  Professor, Brain Research Institute, Niigata University

[1S-13]

Development of an in vitro model of brain neurogenesis in the F0 generation

• Yasuhiro Takashima
  Professor, Center for iPS Cell Research and Application, Kyoto University
• Takafumi Namiki
  Postdoc, Center for iPS Cell Research and Application, Kyoto University
• Keiko Kishimoto
  Researcher, Department of Marmoset Biology and Medicine, Central Institute for Experimental Medicine and Life Science

[1S-14]

Development of a Spatial Proteome Sensor for Astrocyte Activity and Comprehensive Molecular Analysis in the Brain

• Tetsuya Takano
  Associate Professor, Kyushu University Institute for Advanced Study
• Masayuki Sakamoto
  Associate Professor, Kyoto University Graduate School of Biostudies

[1S-15]

Platform for structural analysis of neurodegenerative disease-related proteins using cryo-electron microscopy

• Airi Tarutani
  Researcher, Tokyo Metropolitan Institute of Medical Science
• Masato Hasegawa
  Head, Tokyo Metropolitan Institute of Medical Science

[1S-16]

Establishment of single-cell tissue imaging metabolome analysis technology and elucidation of metabolic mechanisms of brain function changes due to social stress

• Hirotaka Nagai
  Assistant Professor, Kobe University Graduate School of Medicine
• Shuichi Shimma
  Associate Professor, Osaka University Graduate School of Engineering

[1S-17]

Cross-species study of brain aging mechanisms revealed by brain connectome, genes, and individuality

• Takuya Hayashi
  Team Leader, RIKEN Center for Biosystems Dynamics Research
• Toru Ishihara
  Associate Professor, Kobe University Graduate School of Human Development and Environment
• Haruto Takagishi
  Professor, Brain Science Institute, Tamagawa University
• Miho Inoue-Murayama
  Professor, Wildlife Research Center, Kyoto University
• Chihiro Yokoyama
  Professor, Nara Women’s University Faculty Division of Human Life and Environmental Sciences
• BAI Wenjun
  Researcher, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International(ATR)

[1S-18]

Development of tools for visualization and manipulation of synaptic engrams

• Yasunori Hayashi
  Professor, Kyoto University Graduate School of Medicine
• Misa Arizono
  Associate Professor, The Hakubi Center for Advanced Research, Kyoto University
• Takeo Saneyoshi
  Professor, Institute of Science Tokyo School of Life Science and Technology
• Tomoki Matsuda
  Professor, Kitasato University School of Science

[1S-19]

Syntax-based evaluation platform in primate social behavior

• Koki Mimura
  Section chef, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Tomoaki Nakamura
  Associate Professor, The University of Electro-Communication Graduate School of Informatics and Engineering

[1S-20]

Development of genetically encoded fluorescent indicators and intelligent endomicroscopy system for long-term measurements in a freely behaving animal

• Dai Watanabe
  Professor, Kyoto University Graduate School of Medicine

Theme 2

Fundamental understanding of the dynamics of higher brain functions in humans

●: Principal Investigator 〇: Co-Investigator

[2B-01]

Study of functions and dysfunctions of frontal lobe using genome-edited nonhuman primates

• Tadashi Isa
  Professor, Kyoto University Graduate School of Medicine
• Jun Takahashi
  Professor, Center for iPS Cell Research and Application, Kyoto University
• Haruhisa Inoue
  Professor, Center for iPS Cell Research and Application, Kyoto University
• Ryo Sasaki
  Professor, National Institute for Physiological Sciences, Natural Institute of Natural Science
• Tomoyuki Tsukiyama
  Associate Professor, Research Center for Animal Life Science, Shiga University of Medical Science

[2B-02]

Study on the understanding and application of the neural basis of human predictive function

• Takanori Uka
  Professor, University of Yamanashi Graduate School of Medicine
• Naoto Kunii
  Associate Professor, Department of Neurosurgery, Jichi Medical University
• Kenji Kirihara
  Associate Professor, The University of Tokyo Center for Coproduction of Inclusion, Diversity and Equity
• Seijiro Shimada
  Lecturer, The University of Tokyo Hospital

[2B-03]

Similarity and diversity of brain function in genetically identical primates

• Kenichi Ohki
  Professor, The University of Tokyo Graduate School of Medicine
• Tomonari Murakami
  Assistant Professor, The University of Tokyo Graduate School of Medicine
• Takayuki Hashimoto
  Assistant Professor, The University of Tokyo Graduate School of Medicine
• Shogo Matoba
  Senior Research Scientist, RIKEN BioResource Research Center
• Yoko Kurotaki
  Deputy Director, Central Institute for Experimental Medicine and Life Science

[2B-04]

Elucidation of the cortical-subcortical brain dynamics that cause depressive symptoms and cognitive dysfunction using human multidimensional longitudinal data and verification in a primate model

• Go Okada
  Professor (Special Recognition), Hiroshima University Graduate School of Biomedical and Health Sciences
• Ayumu Yamashita
  Visiting Researcher, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institutes International
• Yuki Sakai
  Director, Vice President・Chief Medical Officer, XNef, Inc.
• Takafumi Minamimoto
  Deputy Director, Advanced Neuroimaging Center, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology

[2B-05]

Dynamic neural circuits for elementary symbolic binding in humans and non-human primates: multidimensional tests of a disinhibition hypothesis

• Isao Hasegawa
  Professor, Niigata University School of Medicine
• Atsuhiko Iijima
  Professor, Niigata University Graduate school of Science and Technology
• Hitoshi Shimada
  Professor, Center for Integrated Brain Function Research, Brain Research Institute, Niigata University
• Takuya Hayashi
  Team Leader, RIKEN Center for Biosystems Dynamics Research
• Takeshi Matsuo
  Chief of Neurosurgery, Tokyo Metropolitan Neurological Hospital
• Kiyoshi Nakahara
  Professor, Research Institute, Kochi University of Technology
• Takafumi Suzuki
  Director of Planning Office, Center for Information and Neural Networks, Advanced ICT Research Institute, National Institute of Information and Communication Technology

[2B-06]

Integrative analysis of social distance dynamics across species

• Hirofumi Morishita
  Director, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Misako Komatsu
  Specially Appointed Associate Professor, Institute of Integrated Research, Institute of Science Tokyo
• Takafumi Minamimoto
  Deputy director, Advanced Neuroimaging Center, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology

[2B-07]

Study of function and dynamics in resting-state functional connectivity dynamics induced by network between hippocampus and cortices

• Takufumi Yanagisawa
  Professor, Osaka university Graduate School of medicine
• Haruhiko Kishima
  Professor, Osaka university Graduate School of medicine
• Khoo Hui Ming
  Assistant Professor, Osaka university Graduate School of medicine
• Yuji Ikegaya
  Professor, The University of Tokyo Graduate School of Pharmaceutical Sciences
• Yasushi Iimura
  Associate Professor, Juntendo University
• Naoto Kunii
  Associate Professor, Department of Neurosurgery, Jichi Medical University
• Seijiro Shimada
  Research Associate, The University of Tokyo Hospital

[2B-08]

Study of emotional valence plasticity towards understanding the neural dynamics of empathy

• Ayako M. Watabe
  Professor, Institute of Clinical Medicine and Research, Research Center for Medical Sciences, The Jikei University School of Medicine
• Shun Hamada
  Assistant Professor, University of Yamanashi Faculty of Medicine
• Manabu Abe
  Associate Professor, Brain Research Institute, Niigata University
• Yuichiro Yada
  Designated Lecturer, Nagoya University Graduate School of Medicine

[2S-01]

Development of Fluorescence Imaging Tools and Elucidation of Frontostriatal Pathways in Non-Human Primates

• Hidetoshi Amita
  Program-Specific Associate Professor, Center for the Evolutionary Origins of Human Behavior, Kyoto University

[2S-02]

Dynamics of Cortical-Subcortical Networks Causally Involved in Anxiety of Uncertainty in Primates

• Ken-ichi Amemori
  Associate Professor, Institute for Advanced Study, Kyoto University
• Satoko Amemori
  JSPS Postdoctoral Fellow, Institute for Advanced Study, Kyoto University
• Naoki Honda
  Professor, Nagoya University Graduate School of Medicine

[2S-03]

Understanding the Basic Rules of Neuronal Function in Hypothermic and Hypometabolic States for Artificial Hibernation

• Ryosuke Enoki
  Associate Professor, Exploratory Research Center on Life and Living Systems(ExCELLS), Natural Institute of Natural Science
• Taiga Takahashi
  Assistant Professor, Tokyo University of Science Faculty of Advanced Engineering

[2S-04]

Roles of “large” and “small” cortico-subcortical loops in dynamics of higher-order brain functions

• Kei Oyama
  Senior researcher, Advanced Neuroimaging Center, National Institutes for Quantum Science and Technology (QST)

[2S-05]

Neural circuit dynamics of special navigation systems

• Ryo Sasaki
  Professor, National Institute for Physiological Sciences, The National Institutes of Natural Sciences

[2S-06]

Neural mechanisms of bottom-up and top-down eye movement

• Mayu Takahashi
  Professor, Tohoku University Graduate School of Medicine

[2S-07]

Understanding the cerebral cortex as a parallel circuit; elucidating construction and operating principles of the canonical circuit to establish an indicator of circuit pathology

• Hisato Maruoka
  Assistant professor, The University of Tokyo Graduate School of Medicine
• Yuta Nariya
  Resident, Department of ophthalmology, Kameda Medical Center

[2S-08]

Dynamics of brain region interaction underlying environmental adaptive behavior

• Kenji Mizuseki
  Professor, Osaka Metropolitan University Graduate School of Medicine

[2S-09]

Integration of neurophysiology and laminar fMRI for measurement of cross hierarchical neural dynamics

• Jiajia Yang
  Professor, Okayama University Graduate School of Interdisciplinary Science and Engineering in Health Systems
• Tatsuya Umeda
  Associate Professor, Kyoto University Graduate School of Medicine
• Hirohiko Imai
  Assistant Professor, Kyoto University Graduate School of Informatics
• Masaki Fukunaga
  Project Professor, National Institute for Physiological Sciences, The National Institutes of Natural Sciences

[2S-10]

Study of the function and development of columnar connectivity in marmoset cerebral cortex

• Akiya Watakabe
  Research Scientist, RIKEN Center for Brain Science

Theme 3

Elucidation of pathological mechanisms of neurological and psychiatric disorders

●: Principal Investigator 〇: Co-Investigator

[3A-01]

Elucidation of multi-layer pathogenesis and therapy development of ALS

• Masahisa Katsuno
  Professor, Nagoya University Graduate School of Medicine
• Koji Yamanaka
  Professor, Research Institute of Environmental Medicine, Nagoya University
• Masahiro Nakatochi
  Associate Professor, Nagoya University Graduate School of Medicine
• Yohei Iguchi
  Lecturer, Nagoya University Hospital
• Satoshi Yokoi
  Associate Professor, Nagoya University Graduate School of Medicine
• Daisuke Ito
  Clinical Fellow, Nagoya University Hospital
• Osamu Kano
  Professor, Toho University Faculty of Medicine School of Medicine

[3A-02]

Elucidation of human neuro-pathological mechanism for subtypes of psychiatric disorders by the co-production of mathematical science and clinical psychiatry

• Shinsuke Koike
  Associate Professor, The University of Tokyo Graduate School of Arts and Sciences
• Tempei Ikegame
  Assistant Professor, The University of Tokyo Hospital
• Shinichiro Nakajima
  Assistant Professor, Keio University School of Medicine
• Tsutomu Takahashi
  Professor, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences
• Shingo Iwami
  Professor, Nagoya University Graduate School of Science
• Yoji Hirano
  Associate Professor, University of Miyazaki Faculty of Medicine
• Yutaka Nakachi
  Assistant Professor, Kumamoto University Graduate School of Medical Science

[3A-03]

Understanding and regulation of glia-immune interaction and abnormal brain proteostasis in tauopathies

• Takashi Saito
  Professor, Nagoya City University Graduate School of Medical Sciences
• Taisuke Tomita
  Professor, The University of Tokyo Graduate School of Pharmaceutical Sciences,
• Takeshi Ikeuchi
  Professor, Brain Research Institute, Niigata University
• Mari Tada
  Professor, Brain Research Institute, Niigata University

[3A-04]

AMPA-PET Imaging Unveils Neural Circuitry Implicated in Dementia Pathology

• Takuya Takahashi
  Professor, Yokohama City University Graduate School of Medicine
• Makoto Higuchi
  Director, Advanced Neuroimaging Center, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology

[3B-01]

Identification and intervention of pathological neural circuits in a marmoset model of Lewy Body Disease

• Hirotaka Onoe
  Professor, Kobe Gakuin University Faculty of Pharmaceutical Sciences
• Akiya Watakabe
  Research Scientist, RIKEN Center for Brain Science
• Norihito Uemura
  Part-time Researcher, Kyoto University Graduate School of Medicine
• Tadashi Isa
  Professor, Kyoto University Graduate School of Medicine

[3B-02]

Elucidation of the universal mechanism of neurological disease pathogenesis by endogenous DNA ligands and cellular senescence and its application to the development of therapeutic strategies

• Kinichi Nakashima
  Professor, Kyushu University Graduate School of Medical Sciences
• Yoshikazu Johmura
  Professor, Cancer Research Institute, Kanazawa University
• Noriyuki Kishi
  Visiting Scientist, RIKEN Center for Brain Science

[3B-03]

Combining tau-network mapping and genetic neuromodulation for elucidating circuit pathology and developing interventional approaches

• Toshiyuki Hirabayashi
  Principal Researcher, Advanced Neuroimaging Center, National Institutes for Quantum Science and Technology
• Hironobu Endo
  Senior Researcher, Advanced Neuroimaging Center, National Institutes for Quantum Science and Technology
• Shinichiro Nakajima
  University Lecturer, Keio University School of Medicine

[3B-04]

Molecular and cellular bases for the major biotypes of schizophrenia

• Sho Yagishita
  Lecturer, The University of Tokyo Graduate School of Medicine
• Kenji Tanaka
  Professor, Keio University School of Medicine
• Hiroki Shiwaku
  Tenure-track Associate Professor, Department of Psychiatry and Behavioral Sciences, Institute of Science Tokyo
• Tetsuya Takano
  Associate Professor, Kyushu University Institute for Advanced Study

[3S-01]

Study of the pathomechanisms of the prosaposin-progranulin functional network involved in Parkinson’s disease

• Yutaka Oji
  Associate professor, Juntendo University Faculty of Medicine

[3S-02]

Elucidating the Accumulation and Propagation Mechanisms of Aβ and Tau Toward Novel Therapeutic Strategies for Neurodegenerative Diseases

• Koji Kamagata
  Senior Associate Professor, Juntendo University Graduate School of Medicine
• Akira Sumiyoshi
  Senior Researcher, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology

[3S-03]

Elucidation of imprinting mechanisms linking Fragile X syndrome and Prader-Willi syndrome

• Takako Kikkawa
  Lecturer, Tohoku University Graduate School of Medicine
• Shohei Ochi
  Assistant Professor, Tohoku University Graduate School of Medicine

[3S-04]

Molecular Pathogenesis Studies of Schizophrenia Heterogeneity: Cross-Sectional and Longitudinal Perspectives

• Hiroki Shiwaku
  Associate Professor, Department of Psychiatry and Behavioral Sciences, Institute of Science Tokyo
• Riichiro Hira
  Associate Professor, Institute of Science Tokyo Graduate School of Medical and Dental Sciences
• Akihiro Funamizu
  Lecturer, Institute for Quantitative Bioscience, The University of Tokyo
• Minako Ito
  Associate Professor, Medical Institute of Bioregulation, Kyushu University

[3S-05]

Study of the earliest intranuclear pathogenesis of the degeneration employing a novel disease model animal of ALS

• Yuji Takahashi
  Director, National Center Hospital, National Center of Neurology and Psychiatry
• Tomohiro Kabuta
  Section Chief, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Tatsuo Mano
  Section Chief, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Satoshi Miyashita
  Section Chief, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Masaki Takao
  Director, National Center Hospital, National Center of Neurology and Psychiatry

[3S-06]

Elucidation of the Pathogenesis and Development of Therapeutics for Parkinson’s Disease with focus on Type 1 Interferon

• Tomoyuki Taguchi
  Program-Specific Assistant Professor, Kyoto University Graduate School of Medicine
• Kazuto Tsukita
  Program-Specific Assistant Professor, Kyoto University Graduate School of Medicine
• Mirei Shirakashi
  Assistant Professor, Kyoto University Hospital

[3S-07]

Facilitation of latent capacity based on the mechanism of functional recovery after stroke.

• Yukio Nishimura
  Project Leader, Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science

[3S-08]

Molecular pathogenesis of autism spectrum disorder using human disease models

• Masaaki Nishiyama
  Professor, Institute for Frontier Science Initiative, Kanazawa University

[3S-09]

Study of the regulatory mechanism of alpha-Synuclein aggregation and propagation by astrocyte

• Hiroshi Hanafusa
  Associate Professor, Nagoya University Graduate School of Science

[3S-10]

Investigation of a novel glutamate synthesis pathway in cortical excitatory neurons and its roles in neural activity

• Yusuke Hirabayashi
  Associate Professor, The University of Tokyo School of Engineering
• Akihiro Funamizu
  Lecturer, Institute for Quantitative Biosciences, the University of Tokyo
• Yoshiho Ikeuchi
  Associate Professor, Institute of Industrial Science, The University of Tokyo

[3S-11]

Common pathological mechanisms across epilepsy, intellectual developmental disorders, and autoimmune neurological disorders

• Yuko Fukata
  Associate professor, Nagoya University Graduate School of Medicine

[3S-12]

Mechanism of neurodegeneration and axonal dysfunction induced by RNA phase transition

• Yasushi Yabuki
  Associate Professor, Institute of Molecular Embryology and Genetics, Kumamoto University

[3S-13]

Mechanisms of remyelination failure in white matter injury

• Reiji Yamazaki
  Assistant Professor, Jichi Medical University School of Medicine

Theme 4

Development of the “digital brain,” and related research platforms utilizing mathematical models

●: Principal Investigator 〇: Co-Investigator

[4B-01]

Inverse correlation search and external digitization of brain information using generative AI

• Yuji Ikegaya
  Professor, The University of Tokyo Graduate School of Pharmaceutical Sciences
• Hirokazu Takahashi
  Professor, The University of Tokyo Graduate School of Information Science and Technology
• Okito Yamashita
  Department Head, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International(ATR)

[4B-02]

Development of mathematical models of brain dynamics for neurodevelopmental disorders through data assimilation

• Keiichi Kitajo
  Professor, National Institute for Physiological Sciences, National Institute of Natural Sciences
• Motoaki Nakamura
  Associate Professor/Deputy Director, Medical Institute of Developmental Disabilities Research, Showa University
• Tomohisa Asai
  Senior Researcher, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International (ATR)
• Shinya Nakamura
  Project Associate Professor, Tohoku University Graduate School of Life Sciences
• Hiroshi Yokoyama
  Assistant Professor, Data Science and AI Innovation Research Promotion Center, Shiga University

[4B-03]

Study of motion and sensation in VR environments

• Yasuharu Koike
  Professor, Institute of Integrated Research, Institute of Science Tokyo
• Hiroyuki Kambara
  Associate Professor, Tokyo Polytechnic University Faculty of Engineering

[4B-04]

Development of Digital Twin of Common Marmoset

• Ken Nakae
  Associate Professor, Exploratory Research Center on Life and Living Systems, Natural Institute of Natural Science
• Takako Miyabe
  Assistant Professor, Center for the Evolutionary Origins of Human Behavior, Kyoto University
• Thomas Diego
  Associate Professor, Kyushu University Graduate School and Faculty of Information Science and Electrical Engineering
• Takaaki Kaneko
  Assistant Professor, National Institute for Physiological Sciences, Natural Institute of Natural Science

[4B-05]

Accelerating large-scale computational neuroscience by LLM

• Riichiro Hira
  Associate professor, Institute of Science Tokyo Graduate School of Medical and Dental Sciences
• Jun Igarashi
  Senior Scientist, RIKEN Center for Computational Science
• Kentaro Inui
  Professor, Tohoku University Graduate School of Information Sciences

[4B-06]

Development of scaling techniques on the complexity of a microcircuit structure across species and resolutions towards building a human digital brain from bottom up

• Tadashi Yamazaki
  Associate Professor, The University of Electro-Communications Graduate School of Informatics and Engineering
• Yoshiyuki Kubota
  Associate Professor, National Institute for Physiological Sciences, Natural Institute of Natural Science
• Jun Igarashi
  Senior Scientist, RIKEN Center for Computational Science

[4B-07]

Mesoscopic level digital brain model toward novel therapeutic interventions for mental disorders

• Yuichi Yamashita
  Section Chief, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Masaki Iwasaki
  Director, National Center Hospital, National Center of Neurology and Psychiatry
• Keisuke Suzuki
  Associate Professor, Center for Human Nature, Artificial Intelligence, and Neuroscience (CHAIN), Hokkaido University

[4S-01]

Study of Virtual Neuromodulation and Virtual Treatment in The Digital Brain

• Takuto Okuno
  Specially appointed assistant professor, Tokyo Metropolitan University Graduate School of Human Health Sciences

[4S-02]

Neural code conversion between individuals and species

• Yukiyasu Kamitani
  Professor, Kyoto University Graduate School of Informatics

[4S-03]

BrainScaler, an AI-powered framework for multi-scale brain modeling

• Gutierrez Carlos Enrique
  Visiting Researcher, Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University

[4S-04]

Functionalize Brain Simulation Network and Deep Learning Model by High-Dimensional Neural Data

• SUN ZHE
  Junior Associate Professor, Juntendo University Faculty of Health Data Science
• Keita Tokuda
  Associate Professor, Juntendo University Faculty of Health Data Science
• Li Chao
  Research Scientist, RIKEN Center for Advanced Intelligence Project
• Gu Xiaowei
  Research Scientist, RIKEN Center for Brain Science
• Joshua Johansen
  Team Leader, RIKEN Center for Brain Science

[4S-05]

Artificial neural network modeling of movement disorders

• Tomohiko Takei
  Professor, Brain Science Institute, Tamagawa University

[4S-06]

Creation of a Digital Atlas of Human Brain Gene Expression as a Basis for Dementia Research

• Mari Tada
  Professor, Brain Research Institute, Niigata University
• Norikazu Hara
  Specially appointed assistant professor, Brain Research Institute, Niigata University

[4S-07]

Development of a data-driven whole brain model for identification of disease etiological mechanisms

• Hiromichi Tsukada
  Associate Professor, Center for Mathematical Science and Artificial Intelligence, Chubu University
• Ken Nakae
  Associate Professor, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences

[4S-08]

Hierarchical cyber brain with genes, circuit, and behavior

• Akihiro Funamizu
  Lecturer, Institute for Quantitative Bioscience, the University of Tokyo
• Hiroki Shiwaku
  Tenure-track Associate Professor, Department of Psychiatry and Behavioral Sciences, Institute of Science Tokyo

[4S-09]

Development of a data-driven mathematical model that elucidates and regenerates the linkage between of abnormal protein accumulation and a glial cell network

• Yuichiro Yada
  Designated Lecturer, Nagoya University Graduate School of Medicine
• Okiru Komine
  Lecturer, Research Institute of Environmental Medicine, Nagoya University

Theme 5

Seeds discovery for developing revolutionary drugs, diagnostic and therapeutic methods

●: Principal Investigator 〇: Co-Investigator

[5A-01]

Dementia-treatment study based on cellular and molecular mechanisms of protective variants

• Haruhisa Inoue
  Professor, Center for iPS Cell Research and Application (CiRA), Kyoto University
• Keiko Imamura
  Program-Specific Research Center Junior Associate Professors, Center for iPS Cell Research and Application (CiRA), Kyoto University
• Takayuki Kondo
  Program-Specific Research Center Junior Associate Professors, Center for iPS Cell Research and Application (CiRA), Kyoto University
• Yukihide Momozawa
  Team Leader, RIKEN Center for Integrative Medical Sciences
• Hiroki Sasaguri
  Unit Leader, RIKEN Center for Brain Science
• Atsushi Hoshino
  Lecturer, Kyoto Prefectural University of Medicine Graduate School of Medical Sciences

[5A-02]

Discovery of brain circuit biomarkers and development of neurofeedback therapy based on generative/adversarial AI and digital brains

• Aurelio Cortese
  Head, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International
• Okito Yamashita
  Head, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International
• Hiroshi Imamizu
  Director, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International
• Mitsuo Kawato
  Director, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International
• Toshiya Murai
  Professor, Kyoto University Graduate School of Medicine
• Ryu-ichiro Hashimoto
  Affiliate Professor, Medical Institute of Developmental Disabilities Research, Showa University
• Hidehiko TAKAHASHI
  Professor, Institute of Science Tokyo Graduate School of Medical and Dental Sciences
• Go Okada
  Professor (Special Recognition), Hiroshima University Graduate School of Biomedical and Health Sciences
• Yuji Ikegaya
  Professor, The University of Tokyo Graduate School of Pharmaceutical Sciences

[5A-03]

Unleashing a New Era: Pioneering Therapies for α-Synucleinopathies

• Nobutaka Hattori
  Professor and Chairperson, Juntendo University Faculty of Medicine
• Taku Hatano
  Senior Associate Professor, Juntendo University Faculty of Medicine
• Yasuyoshi Kimura
  Assistant Professor, Osaka University Graduate School of Medicine
• Hodaka Yamakado
  Research associate professor, Kyoto University Graduate School of Medicine
• Shinji Saiki
  Professor, University of Tsukuba Faculty of Medicine
• Yeon-Jeong Kim
  Assistant Professor, University of Yamanashi Faculty of Medicine

[5B-01]

Multi-layer sequencing of germline, somatic, virus variants accelerate seeds development of autoimmune neurological diseases

• Yukinori Okada
  Professor, The University of Tokyo Graduate School of Medicine
• Noriko Isobe
  Professor, Kyusyu University Graduate School of Medical Sciences
• Tatsusada Okuno
  Associate Professor, Osaka University Graduate School of Medicine

[5B-02]

Development of a comprehensive blood biomarker system capable of assessing the background pathology of dementia using PET as a reference standard

• Kenji Tagai
  Researcher, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST)
• Manabu Ikeda
  Professor, Osaka University Graduate School of Medicine
• Shigeki Hirano
  Associate Professor, Chiba University Graduate School of medicine
• Shunichiro Shinagawa
  Professor, The Jikei University School of Medicine

[5B-03]

Development of Therapeutic Seeds Based on Functional Analysis of Alzheimer’s Disease Causative Genes

• Hideaki Matsui
  Professor, Brain Research Institute, Niigata University
• Yuuki Ishita
  Assistant professor, Brain Research Institute, Niigata University
• Yuki Fujita
  Professor, Shimane University Faculty of Medicine
• Yuichi Wakana
  Assistant Professor, Tokyo University of Pharmacy and Life Sciences School of Life Sciences

[5S-01]

Proof of concept study of data-driven novel therapeutic agents for obsessive-compulsive disorder and their indication expansion

• Nozomi Asaoka
  Assistant professor, Kyoto University Graduate School of Medicine
• Toshiya Murai
  Professor, Kyoto University Hospital
• Hirotsugu Kawashima
  Assistant Professor, Kyoto University Hospital
• Yasunori Hayashi
  Professor, Kyoto University Graduate School of Medicine

[5S-02]

Analysis of plasma components involved in the development of dementia and development of transplantation therapy

• Nariko Arimura
  Associate Professor, Tohoku University Graduate School of Pharmaceutical Science
• Goro Sashida
  Professor, International Research Center for Medical Sciences, Kumamoto University
• Satoshi Miyashita
  Section Chief, National Institute of Neuroscience, National Center of Neurology and Psychiatry
• Tomoki Nishioka
  Lecturer, Institute for Comprehensive Medical Science, Fujita Health University

[5S-03]

Development of a novel therapy for tauopathy: a MARK4 inhibitor

• Kanae Ando
  Associate Professor, Tokyo Metropolitan University School of Science

[5S-04]

Study of Immune Cells in Autism Spectrum Disorders

• Minako Ito
  Associate Professor, Medical Institute of Bioregulation, Kyushu University
• Manabu Makinodan
  Associate Professor, Fujita Health University School of Medicine

[5S-05]

Development of Novel Brain Disease Therapy Based on the Bioprotective Effects of Senescent Microglia

• Hiroshi Ohnishi
  Professor, Gunma University Graduate School of Health Sciences
• Takashi Matozaki
  Project Professor, Kobe University Graduate School of Medicine

[5S-06]

Exploratory research on suppression of amyloid β aggregation by Auger electrons

• Masahiro Ono
  Professor, Kyoto University Graduate School of Pharmaceutical Sciences

[5S-07]

Development of antisense oligonucleotides that enable highly efficient RNA editing at pathogenic point mutations

• Yukio Kawahara
  Professor, Osaka University Graduate School of Medicine
• Yuki Kato
  Associate Professor, Osaka University Graduate School of Medicine
• Taisuke Nakahama
  Assistant Professor, Osaka University Graduate School of Medicine

[5S-08]

Therapeutic Strategy on neurodegenerative pathology by microglial regulation

• Kimitoshi Kimura
  Program-Specific Junior Associate Professor, Kyoto University Graduate School of Medicine
• Kazunari Aoki
  Assistant Professor, Institute for Life and Medical Sciences, Kyoto University
• Kazuto Tsukita
  Program-Specific Assistant Professor, Kyoto University Graduate School of Medicine

[5S-09]

The Potential of Olfaction in an Aging Society: Establishing Methods for Predicting and Preventing Dementia Through Scent

• Haruki Takeuchi
  Professor, The University of Tokyo Graduate School of Science

[5S-10]

Study on the role of progressive complex ubiquitination in neurodegenerative diseases-associated inclusions and the disease-suppressing effects of ubiquitin ligase inhibitors

• Fuminori Tokunaga
  Professor, Osaka Metropolitan University Graduate School of Medicine

[5S-11]

Study of EEG-NF to treat phantom limb pain

• Takufumi Yanagisawa
  Professor, Osaka University Graduate School of medicine

Practical Application Support Team

Practical Application Support Team

●: Principal Investigator 〇: Co-Investigator

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