Dysregulation of the dopaminergic system is postulated to play a crucial role in the etiology of several neurological and psychiatric conditions, including Parkinson's disease, schizophrenia, and attention deficit hyperactivity disorder (ADHD). This study proposes to substantially enhance the spatial resolution of dopamine measurements by employing a novel optical fiber technology, enabling simultaneous optical measurements across multiple subregions using a single fiber. Moreover, this innovative recording technique will be extended to encompass multiple brain regions. The anticipated outcomes of this research are expected to make significant contributions to human health through improved dopamine recording efficiency, uncovering of new mechanistic insights, and acceleration of drug discovery efforts targeting dopamine and its associated molecular pathways.