Dementia is a disease marked by a persistent decline in brain function, affecting memory, judgment, and other cognitive abilities. Alzheimer's disease is the most common form of dementia. While there is currently no cure, early diagnosis is crucial. Recently, research has focused on how blood components impact brain function. Studies have shown that body fluids from young mice can restore cognitive function in aged mice. This research aims to investigate how genetic changes in bone marrow cells influence cognitive function, ultimately seeking to identify blood components and potential treatments that may improve outcomes for individuals with dementia in the future.