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Dec 03, 2025
- Press
Derivation of embryonic stem cells from cloned blastocysts using improved somatic cell nuclear transfer in common marmosetsResearchers at RIKEN BRC and CIEM have, for the first time, established embryonic stem cells from somatic cell…
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Nov 12, 2025
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Single-cell synaptome mapping of endogenous protein subpopulations in mammalian brainA collaborative team led by Drs. Uchigashima and Mikuni (Niigata University) developed a new technology for si…
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Nov 05, 2025
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The astrocytic ensemble acts as a multiday trace to stabilize memoryThis study reveals that astrocytic ensembles serve as multiday traces for memory stabilization. By capturing t…
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Oct 23, 2025
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Apusomonad rhodopsins: A new family of ultraviolet to blue light–absorbing rhodopsin channelsWe have discovered over ten novel microbial rhodopsins—named Apusomonad rhodopsins—from protists, and demonstr…
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Oct 03, 2025
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Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8+ T cellsFingolimod reduces peripheral T cells but increases brain CD8⁺ T cells in P301S-tau transgenic mice, exacerbat…
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Sep 09, 2025
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FMR1 Mutant Marmosets Show Fragile X Syndrome PhenotypesFragile X syndrome (FXS), caused by FMR1 silencing, was modeled in common marmosets carrying FMR1 mutations. M…
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Aug 27, 2025
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SeeThrough: a rationally designed skull clearing technique for in vivo brain imagingA collaborative team led by Drs. Mikuni, Tainaka (Niigata University) and Murayama (RIKEN CBS) developed SeeTh…
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Aug 07, 2025
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Aversive experiences induce valence plasticity of instructive signals to change future learning rules in micePast experiences can alter emotional valence, such as pain, but the neuronal mechanisms remain unclear. A rese…
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May 01, 2025
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Type I collagen secreted in white matter lesions inhibits remyelination and functional recoveryThere is still no effective treatment for white matter injury. In addition, the mechanisms underlying impaired…
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Mar 17, 2025
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Asymmetric projection of introspection reveals a behavioural and neural mechanism for interindividual social coordinationAn international research group led by Kentaro Miyamoto (RIKEN Center for Brain Science) has psychologically i…
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Feb 25, 2025
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Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologiesXPO7 haploinsufficiency increases risk of schizophrenia. The research group discovered that Xpo7 haploinsuffic…
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Feb 04, 2025
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Amygdalo-cortical dialogue underlies memory enhancement by emotional associationPositive emotional association enhances perceptual memory The research group uncovered how a positive experien…
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Dec 06, 2024
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Evolutionary changes leading to efficient glymphatic circulation in the mammalian brainProf. Hiroshi Kawasaki and associate prof. Satoru Okuda and colleagues of Kanazawa University uncovered sulcus…
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Dec 06, 2024
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Orthogonalization of spontaneous and stimulus-driven activity by hierarchical neocortical areal network in primatesThe research group compared the spatial patterns of spontaneous activity and visual responses in the visual co…
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Nov 08, 2024
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Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autismUsing resting-state fMRI and a machine learning method, Dr. Itahashi and colleagues identified resting-state f…
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Nov 08, 2024
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Characterization of patients with major psychiatric disorders with AMPA receptor positron emission tomographyA research team led by Professor Takuya Takahashi from the Department of Physiology at Yokohama City Universit…