Development of a Novel Device for Evaluating Myelin Repair and Its Application for Drug Discovery

Elucidation of the aging mechanism of fibroblasts in cerebrovascular diseases and its therapeutic application

Development of an ALS/FTLD Therapy Using a Long-Acting Nucleic Acid Drug That Targets TDP-43 Phase Separation

Identification of extreme cases by stratification of psychiatric disorders and research on drug discovery seeds using highly validated animal and cellular models based on extreme cases

Innovative Early Diagnostic Development Using Integrated αSynuclein-PET/Longitudinal MRI and Acceleration of Disease-Modifying Therapy via Molecular Pathology-Based Trial-Ready Cohort in Multiple System Atrophy

Identification of targets for therapeutic intervention in sporadic amyotrophic lateral sclerosis and development of drug seeds: through integrated analysis of large-scale clinical genomic information and patient-derived iPS cells/motor neurons

Development of diagnostic and therapeutic methods based on high-risk variants of autistic spectrum disorders using IGF-1 receptor agonists as a starting point

Development of a method for cross-species brain transformation

Circuit Model of Cell Death Induced Decision Making Deficiency

Understand the hallucination and delusion mechanism of schizophrenia from replay brain activities using a connectome dynamics model

A Digital Twin Brain for Simulating Mental Disorder Treatments Across Micro and Macro Scales

Human Brain-Body Simulation Contributing to the Elucidation of Neural Mechanisms in SCA6