Establishment of somatic cell nuclear transfer (SCNT) technology in common marmosets

Research period : 2021-2023
Principal Investigator
的場 章悟

Shogo Matoba

RIKEN BioResource Research Center

Somatic cell nuclear transfer (SCNT) technology, which can rapidly expand the number of valuable disease model organisms, could be a fundamental technology for research of non-human primates with a long breeding period. Therefore, in this study, we aim to establish SCNT technology to produce cloned animals of common marmosets. We will develop novel developmental engineering technologies such as efficient egg retrieval, nuclear transfer, and epigenome editing in marmosets, and use the established technologies to obtain cloned offspring of Parkinson's disease model marmosets.

  • Yoko Kurotaki

    Center of Basic Technology in Marmoset, Central Institute for Experimental Animals