Organization
(As of November 1, 2017)
Program Supervisor
Shigeo Okabe(Graduate School of Medicine,The University of Tokyo)
Program Officers
Tetuya Matsuda(Brain Science Institute, Tamagawa University)
Toshihasa Ohtsuka(Graduate School of Medicine, The University of Yamanashi)
Watanabe Masahiko(Department of Anatomy Hokkaido University School of Medicine)
Project Leaders
Atsushi Miyawaki(RIKEN Center for Brain Science)
Hideyui Okano(RIKEN Center for Brain Science/School of Medicine, Keio University)
Central Institutes
Structure and activity mapping of primate brain
Development of novel cutting edge technologies
Core Institute (RIKEN)
Team A
Structure and functional mapping of the non-human primate brain
- Hideyuki Okano
CBS, Marmoset Neural Architecture
School of Medicine, Keio University - Tetsuo Yamamori
CBS, Molecular Analysis of Higher Brain Function - Noritaka Ichinohe
CBS, Molecular Analysis of Higher Brain Function - Tomomi Shimogori
CBS, Molecular Mechanisms of Thalamus Development - Atsushi Iriki
CBS, Symbolic Cognitive Development - Takaomi C. Saido
CBS, Proteolytic Neuroscience - Takuya Hayashi
Brain Connectomics Imaging Team
Center for Biosystems Dynamics Research - Partha Mitra
CBS, Marmoset Neural Architecture
Cold Spring Harbor Laboratory
Team B
Development of novel, cutting-edge technologies that support brain mapping
- Atsushi Miyawaki
CBS, Molecular Analysis of Higher Brain Function - Keiji Tanaka
CBS, Cognitive Brain Mapping - Yukiko Goda
CBS, Synaptic Plasticity and Connectivity - Taro Toyoizumi
CBS, Neural Computation and Adaption - Shigeyoshi Fujisawa
CBS, Systems Neurophysiology - Masanori Murayama
CBS, Behavioral Neurophysiology - Tomoki Fukai
CBS, Neural Circuit Theory - Yoko Yamaguchi
CBS, Neuroinformatics Japan Center - Hideo Yokota
RAP, Image Processing Research Team
Partner Institutes
(Keio univ./Kyoto univ.)
Innovative approaches for the compilation of non-human primate brain map
- Shinsuke Shibata
Keio University School of Medicine, Electron Microscope Laboratory
Neural networks underlying higher brain functions in common marmosets
- Katsuki Nakamura
Prime Research Institute, Kyoto University
Clinical Research Group
Technology development for the overcoming of psychiatric and neurological disorders in humans
Management Team
Translation between brain maps in primates and brain circuits in patients with neuropsychiatric disorders using integrative neuroimaging data resources
- Kiyoto Kasai
Graduate School of Medicine,
The University of Tokyo
Elucidation of pathological neural network via imaging genetics analysis for mental disorders
- Norio Ozaki
Graduate School of Medicine,
Nagoya University,Department of Psychiatry&
Department of Child and Adolescent Psychiatry
Elucidation of neural circuit responsible for cognition and behavior in disease pathology
- Ryota Hashimoto
United Graduate School of Child Development, Osaka University
The research on neural circuit of neuropsychiatric disorders – molecular mechanism and modeling
- Tetsuya Suhara
National Institutes for Quantum and Radiological Science and Technology,
National Institute of Radiological Sciences
Acquisition of detailed functional and structural brain images of human healthy subjects for promotion of understanding brain circuits of the marmoset, a new animal model for neuropsychiatric diseases
- Kenji Matsumoto
Brain Science Institute, Tamagawa University
Identification of disease-common neural circuit abnormalities
- Tetsuo Kobayashi
Graduate School of Engineering,
Kyoto University
Disease Research Team
(Neuropsychiatric Disorders)
Translation between brain maps in primates circuits in patients with neuropsychiatric disorders using integrative neuroimaging data resources
- Kiyoto Kasai
Graduate School of Medicine,
The University of Tokyo
Elucidation of pathological neural network via identification of rare genomic variants associated with mental disorders
- Norio Ozaki
Graduate School of Medicine,
Nagoya University, Department of Psychiatry & Department of Child and Adolescent Psychiatry
Elucidation of neural circuit responsible for cognition and behavior in disease pathology
- Ryota Hashimoto
United Graduate School of Child Development,
Osaka University
The research on neural circuit of neuropsychiatric disorders – molecular mechanism and modeling
- Tetsuya Suhara
National Institutes for Quantum and Radiological Science and Technology,
National Institute of Radiological Sciences
Investigation of altered neural circuits in autism spectrum disorder and schizophrenia using multimodal MRI and development of cross-species translatable measures of brain functions
- Ryuichiro Hashimoto
Medical Institute of Developmental Disabilities Research,
Showa University Karasuyama Hospital
Neural pathways for saliency detection during free-viewing
- Masatoshi Yoshida
National Institute for Physiological Science,
National Institutes of Natural Sciences
Elucidation of neural networks associated with mood disorders by analyzing neuroimaging
- Yasumasa Okamoto
Graduate School of Biomedical Sciences,
Hiroshima University
Analysis of molecular-motor in animal models
- Yosuke Takei
University of Tsukuba
Disease Research Team
(Cerebrovascular Disease and others)
Translational research for neuronal circuitry pathologies of Parkinson’s and cerebrovascular diseases
- Ryosuke Takahashi
Department of Neurology
Kyoto University Graduate School of Medicine
Identification of mechanism for motor paralysis and higher brain dysfunction after cerebrovascular disorder,and establishment the translatable biomarkers for their functional recovery using nonhuman primate model
- Tadashi Isa
Department of Neuroscience,
Graduate School of Medicine, Kyoto University
Elucidation of injured neural networks and their compensatory mechanisms due to the acute and chronic neurological disorders
- Miho Murata
National Center Hospital,
National Center of Neurology and Psychiatry
Development of PET probes to detect synaptic proteins
- Takuya Takahashi
Yokohama City University,
Graduate School of Medicine
The ultrastructural identification of translatable biomarkers for the diagnosis of the early stages of Parkinson’s disease and related disorders
- Masato Koike
Juntendo University,
Graduate School of Medicine
The analysis of pathological neural networks in the patients with movement disorders and animal disease models
- Toshiki Yoshimine
Global Center for Medical Engineering and Informatics, Osaka University
Disease Research Team
(Neurodegenerative Disease)
Comprehensive researches to elucidate neuro-network dysfunctions in neurodegenerative dementia
- Hitoshi Okazawa
Medical Research Institute / Center for Brain Integrative Research,
Tokyo Medical and Dental University
Identification of damaged neuronal circuits in very early Alzheimer disease patients and elucidation of molecular mechanism of tau pathology spreading
- Taisuke Tomita
Graduate School of Pharmaceutical Sciences,The University of Tokyo
Developing innovative therapeutic interventions for frontotemporal lobar degeneration based on the elucidation of neural circuit disruption
- Gen Sobue
Graduate School of Medicine,Nagoya University
Multiple molecular and radiological analysis of Parkinson’s disease pathogenesis based on patients and animal models
- Nobutaka Hattori
Juntendo University,
Graduate School of Medicine
Detection of a key neural circuit in very early stage of Alzheimer’s disease
- Hiroshi Matsuda
Integrative Brain Imaging Center,
National Center of Neurology and Psychiatry
Translatable imaging and mechanistic controls of a pathological cascade in age-related neurodegenerative conditions
- Makoto Higuchi
National Institutes for Quantum and Radiological Science and Technology,
National Institute of Radiological Sciences
Molecular mechanisms of spreading of TDP-43 pathology
- Masato Hasegawa
Tokyo Metropolitan Institute of Medical Science,
Department of Dementia and Higher Brain Function
Technology Development Group
Development of novel cutting edge technologies
Development of novel cutting edge technologies
Ultra-thin Electronic Sensor System for Marmoset’s Brain Signal measurement
- Tsuyoshi Sekitani
The Institute of Scientific and Industrial Research,
Osaka University
A novel multi-neuronal recording with optogenetic identification of axonal projections
- Yoshikazu Isomura
Brain Science Institute,
Tamagawa University
Computational frameworks for multi-scale models using structural and functional brain map data
- Kenji Doya
Neural Computation Unit,
Okinawa Institute of Science and Technology
Graduate University
Development of the marmoset embryo-manipulating technologies for efficient generation of knock-in animals and reduction of generation interval
- Atsu Aiba
Graduate School of Medicine,
The University of Tokyo - Atsuo Ogura
Bioresource Engineering Division,
RIKEN BioResource Research Center
Development of optical techniques to manipulate and measure cortical circuits with higher brain functions
- Masanori Matsuzaki
Graduate School of Medicine,
The University of Tokyo
Fast 3D recording of neuronal activity and long-term imaging of activity traces through development of innovative probing technologies
- Haruhiko Bito
Graduate School of Medicine,
The University of Tokyo - Kazuo Kitamura
Graduate School Department of Interdisciplinary Research,
University of Yamanashi
Development of super-resolution multi-photon microscopy by utilizing a novel semiconductor based light source
- Tomomi Nemoto
Research Institute for Electronic Science,
Hokkaido University - Hiroyuki Yokoyama
New Industry Creation Hachery Center,
Tohoku University
New Technology Innovation
Multimodal multi-scale functional mapping of marmoset brain and development of functional mapping at ultra-fine scale
- Kenichi Ohki
Graduate School of Medicine,
The University of Tokyo
Analyze structures and functions of marmoset brains by multi-scale and multi-modal approaches
- Atsushi Nambu
National Institute for Physiological Sciences,
National Institutes for Natural Sciences - Hajime Mushiake
School of Medicine,
Tohoku University
AAV vector-mediated cell type-specific gene knock-down / knock-out in marmoset CNS in vivo
- Hirokazu Hirai
Graduate School of Medicine,
Gunma University
Mapping the structure and function of the cortico-basal ganglia network in marmosets by use of pathway-specific labeling and manipulation technology
- Kazuto Kobayashi
School of Medicine,
Fukushima Medical University - Miwako Yamasaki
Faculty of Medicine,
Hokkaido University
Production of knockout marmoset using spermatogenic cells
- Takashi Shinohara
Graduate School of Medicine,
Kyoto University
Zoom-in to the ultrastructure level from the whole brain level using a tissue-clearing method as the cornerstone
- Hiroyuki Hioki
School of Medicine,
Juntendo University - Takahiro Furuta
Graduate School of Dentistry,
Osaka University
Development of neural circuit tracing for mapping the connectome in the common marmoset
- Fumitaka Osakada
Graduate School of Pharmaceutical Sciences,
Nagoya University
Development of innovative method for an all-optical electrophysiology to measure and manipulate neural activity.
- Masayuki Sakamoto
Graduate School of Medicine,
The University of Tokyo - Yuki Sudo
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,
Okayama University
Development of innovative wide-view mapping of synaptic ensemble in the psychiatric model
- Akiko Hayashi-Takagi
Lab of Medical Neuroscience,
Institution of Molecular and Cellular Regulation,
Gunma University
Development of 3D imaging and analysis pipeline for marmoset brain
- Hiroki R. UEDA
Graduate School of Medicine,
The University of Tokyo
Super-multicolor labeling for automatic reconstruction of neuronal circuits
- Takeshi Imai
Graduate School of Medical Sciences,
Kyushu University
Development of a method for high speed and high resolution whole-brain imaging in primates
- Hitoshi Hashimoto
Graduate School of Pharmaceutical Sciences,
Osaka University