Computational frameworks for multi-scale models using structural and functional brain map data

Principal Investigator
銅谷 賢治

Kenji Doya

Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University

We will develop computational frameworks for constructing multi-scale neural models that link cellular and network dynamics to behavioral and cognitive functions by utilizing large-scale anatomical and physiological data sets. Specific targets are the following: 1) Estimation of cellular and synaptic parameters from connectome, imaging, and electrode recording data. 2) Automated reduction of conductance-based models to integrate-and-fire models, and spiking neural network models to population firing rate models. 3) Application and validation of the above methods with the data being produced by the Brain/MINDS project.