Acoustic-optical technologies for investigating deep brain area

Research period : 2019-2023
Principal Investigator
中川 桂一

Keiichi Nakagawa

Graduate School of Engineering, The University of Tokyo

To guide light to deep tissue sites in the brain, we create optical fiber or waveguide-like refractive index profiles inside brain tissues in a non-invasive manner. We will use spatiotemporal control of refractive index profiles of brain tissues by the pressure fields of nonlinear acoustic waves. We will develop novel acoustic-optical techniques based on optical and acoustical engineering technologies that enhance the performance of conventional optical stimulation and measurement methods such as optogenetics, fluorescence imaging, near-infrared spectroscopy, and whole-brain analysis with transparent brains.

  • Shu Takagi

    School of Engineering, The University of Tokyo
  • Eiji Okada

    Faculty of Science and Technology, Keio University
  • Hiroshi Fukuoka

    Department of Mechanical Engineering, National Institute Of Technology, Nara College