A Mesoscale Circuit Map of the Marmoset Brain


Partha Mitra

Cold Spring Harbor Laboratory

The goal to obtain a mesoscale circuit map of the brain of the Marmoset, using injections of neuronal tracer substances placed on a systematic grid designed to cover one hemisphere of the brain. Both viral and classical tracer substances, transporting in anterograde and retrograde directions, will be used to map the inputs/outputs of brain regions. The brains will be processed in a high throughput neurohistology pipeline, producing a collection of whole-brain digital light microscopic data sets. The raw data will be made publicly available through a data portal, as well as subjected to computational neuroanatomical analysis, to obtain a mesoscale circuit map of the Marmoset brain. This sub-component of the Brain/MINDS initiative is an international collaborative effort centered at Riken BSI.